| Burt Lancaster (Wyatt Earp) |
| Kirk Douglas (Doc Holliday) |
| Rhonda Fleming (Laura Denbow) |
| Jo Van Fleet (Kate Fisher) |
| John Ireland (Johnnie Ringo) |
| Lyle Bettger (Ike Clanton) |
| Frank Faylen (Cotton Wilson) |
| Earl Holliman (Charles Bassett) |
| Ted de Corsia (Shangai Price) |
| Dennis Hopper (Billy Clanton) |
| Whit Bissell (John P. Clum) |
| George Mathews (John Shanssey) |
| John Hudson (Virigl Earp) |
| DeForrest Kelley (Morgan Earp) |
| Lee Van Cleef (Ed Bailey) |
| Kenneth Toby (Bat Masterson) |
| Dorothy Abbott |