| Richard Gere (Dixie Dwyer) |
| Gregory Hines (Dalbert Williams) |
| Diane Lane (Vera Cicero) |
| Lonette McKee (Lila Rose Oliver) |
| Bob Hoskins (Owney Madden) |
| James Remar (Dutch Schultz) |
| Nicolas Cage (Vincent Dwyer) |
| Allen Garfield (Abbadabba Berman) |
| Fred Gwynne (Franchy de Mange) |
| Gwen Verdon (Tish Dwyer) |
| Lisa Jane Persky (Frances Flegenheimer) |
| Maurice Hines (Clay Williams) |
| Julian Beck (Sol Weinstein) |
| Novella Nelson (Mme St Clair) |
| Larry Fishburne (Bumpy Rhodes) |
| John Ryan (Joe Flynn) |
| Tom Waits (Irving Stark) |
| Ron Karabastos (Mike Best) |
| Glenn Withrow (Ed Popke) |
| Jennifer Grey (Pasty Dwyer) |
| Wynonna Smith (Winnie Williams) |
| Thelma Carpenter (Norma Williams) |
| Chares "Honi" Coles (Sugar Coates) |
| Larry Marshall (Cab Calloway) |
| Joe Dalessandro (Lucky Luciano) |