| Howard Stern (Howard Stern) |
| Robin Quivers (Robin Quivers) |
| Mary McCormack (Alison Stern) |
| Fred Norris (Fred Norris) |
| Paul Giamatti (Kenny) |
| Gary Dell'Abate (Gary Dell'Abate) |
| Jackie Martling (Jackie Martling) |
| Carol Alt (Gloria) |
| Richard Portnow (Ben Stern) |
| Kelly Bishop (Ray Stern) |
| Henry Goodman (Moti) |
| Jonathan Hadary (Griff) |
| Paul Hecht (Ross Buckingham) |
| Allison Janney (Dee Dee) |
| Michael Murphy (Roger Erlick) |
| James Murtaugh (Payton) |
| Reni Santoni (Vallesecca) |
| Lee Wilkof (Marvin Mamoulian) |
| Melanie Good (Brittany Fairchild) |
| Theresa Lynn |
| Amber Smith (Julie) |
| Althea Cassidy |
| Jenna Jameson (Mandy) |
| Bobby Borriello |
| Michael Maccarone |
| Matthew Friedman |
| John Michael Bolger |
| John Stamos (John Stamos) |
| Chris Barron (Chris Barron) |
| Flava Flav (Flavor Flav) |
| Hammer (M.C. Hammer) |
| Ted Nugent (Ted Nugent) |
| Ozzy Osbourne (Ozzy Osbourne) |
| John Popper (John Popper) |
| Slash (Slash) |
| Renee Suran (Renee Suran) |
| Dee Snider (Dee Snider) |
| Tiny Tim (Tiny Tim) |
| Steven Gilborn (L'agent d'Howard) |
| Curtis McClarin |
| Richard B. Shull |
| Evan Roberts (Elliot) |
| Gabriel de Silva (Herbie) |
| Jennifer Gareis |
| Mandy Steckelberg |
| Ali Marsh |
| Scott Cohen |
| James Villemaire |
| Wendy Hoopes (Elyse) |
| Richard Russell Ramos |
| Gordon Joseph Weiss |
| Allison Furman |
| Julie Gawkowski (Patricia Fonfara) |
| Davenia McFadden (L'infirmière) |
| Michael Gwynne (Le duc du Rock) |
| Irene DeCook |
| Jordan Derwin |
| Silas Weir Mitchell |
| Stuart Rudin |
| Richard Ziman |
| Adam LeFevre |
| Janine Lindemulder |
| Scott Lawrence |
| Christine Tucci (La doctoresse) |
| Kim Chan (Une serveuse) |
| Nick Wyman (Douglas Kiker) |
| Stephen Pearlman |
| Catherine Wolf |
| Tom Tammi |
| Luke Reilly |
| Rick Levi (Un avocat) |
| Peter Jacobson (Un avocat) |
| Leslie Bibb |
| Joanne Camp |
| Peter Maloney |
| Sarah Zinsser |
| Barry Papick |
| David Letterman (David Letterman) |
| Christine Toy |
| Alison Stern |
| Brian Johnson (Brian Johnson du groupe AC-DC) |
| Angus Young (Angus Young du groupe AC-DC) |
| Malcolm Young (Malcolm Young du groupe AC-DC) |
| Phil Rudd (Phil Rudd du groupe AC-DC) |
| Cliff Williams (Cliff Williams du groupe AC-DC) |
| Susan Pratt |
| Sasha Martin (Une des filles d'Howard) |
| Sarah Jane Hyland (Une des filles d'Howard) |
| 'Stuttering' John Melendez (John Melendez) |
| George 'Crackhead Bob' Harvey (Crackhead Bob) |
| Nicole Bass (Nicole Bass) |
| Camille Donatacci |
| Danna Bradley |
| Seth Silver |
| Carrie Flaska |
| Steve Ballot |
| Brian Costantini |
| Barnett Milton Lloyd |
| Aimee Luzier (La voix de Betty Jean Rushton) |
| Demetria Bailey |
| Lawrence Cioppa (Le père d'Alison) |
| Rico Racine |
| Geraldine Scalia |
| Stewart J. Zully (Dicky Davis) |
| Mary Lou Allgood |
| Alley Baggett |
| Damian Bailey |
| Janai P. Canada |
| John Capo |
| Garrett Cassell |
| Wilson Cleveland |
| Joe Tom Collins (Un étudiant au collège) |
| Joseph Corredor |
| Peter Costanza |
| Bashirrah Creswell (Teresa) |
| Gregory d'Angelo |
| Christopher del Gaudio |
| Steve DiGennaro |
| Mary Dimino |
| Brother Eden Douglas |
| Patrick Coleman Duncan |
| Stuart Ellis |
| Edie Falco |
| Shawn P. Farrell |
| Mia Farrow (Mia Farrow) |
| Al Giordano |
| Tommy Grillo |
| Larry Guardino |
| Marianne Hettinger (Mary) |
| Barry Hirschberg |
| Sonia Kazarova |
| Bradley Kell |
| James Koons |
| James Krieger |
| Stacey Louis |
| Marshall Dancing Elk Lucas |
| Frank Lukacs |
| Katie MacIntosh |
| Kevin McFeeley |
| Bonnie Monaghan |
| Jennifer Moody |
| James Murray |
| Joy Newman |
| Francesco Paladino |
| Iggy Pop (Iggy Pop) |
| Sal Rinella |
| Kevin Scullin |
| Kennen Sisco |
| David Sontag |
| Matilda Szydagis |
| Larry Tobias |
| Emmanuel Todorov |
| Christopher Tracy |
| JD Walters |
| Chris White |
| Wendy Whoppers |
| Eric Attio (La pilote d'avion - Scènes coupées au montage) |