| Anthony Mackie (John Henry 'Jack' Armstrong) |
| Kerry Washington (Fatima Goodrich) |
| Ellen Barkin (Margo Chadwick) |
| Monica Bellucci (Simona Bonasera) |
| Jim Brown (Geronimo Armstrong) |
| Ossie Davis (Le juge Buchanan) |
| Jamel Debbouze (Doak) |
| Brian Dennehy (Le président Billy Church) |
| Woody Harrelson (Leland Powell) |
| Bai Ling (Oni) |
| Lonette McKee (Lottie Armstrong) |
| Paula Jai Parker (Evelyn) |
| Q-Tip (Vada Huff) |
| Dania Ramirez (Alex Guerrero) |
| John Turturro (Don Angelo Bonasera) |
| Chiwetel Ejiofor (Frank Wills) |